array(1) { [0]=> string(6) "mobile" }

Julkaisut

Sydänsairaalan julkaisut vuonna 2018

Ahola A, Pölönen RP, Aalto-Setälä K, Hyttinen J.: Simultaneous Measurement of Contraction and Calcium Transients in Stem Cell Derived Cardiomyocytes. (Ann Biomed Eng 2018:46(1):148-158. doi: 10.1007/s10439-017-1933-2)

Antiperovitch P, Zareba W, Steinberg JS, Bacharova L, Tereshchenko LG, Farre J, Nikus K, Ikeda T, Baranchuk A.: Proposed In-Training Electrocardiogram Interpretation Competencies for Undergraduate and Postgraduate Trainees. (J Hosp Med. 2018 Mar 1;13(3):185-193. doi: 10.12788/jhm.2876.)

Aula H, Skyttä T, Tuohinen S, Luukkaala T, Hämäläinen M, Virtanen V, Raatikainen P, Moilanen E, Kellokumpu-Lehtinen P.: Decreases in TGF-ß1 and PDGF levels are associated with echocardiographic changes during adjuvant radiotherapy for breast cancer. (Radiat Oncol 2018:13(1):201. doi: 10.1186/s13014-018-1150-7)

Barbosa-Barros R, Pérez-Riera AR, Koivula K, de Carvalho Santos J, de Abreu LC, Nikus K.: Acute coronary syndrome of very unusual etiology. (Ann Noninvasive
Electrocardiol. 2018 Sep;23(5):e12531. doi: 10.1111/anec.12531)

Bihlmeyer NA, Brody JA, Smith AV, et al: ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals. (Circ Genom Precis Med. 2018 Jan;11(1):e001758. doi: 10.1161/CIRCGEN.117.001758)

Davies G, Lam M, Harris SE, et al: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. (Nat Commun. 2018 May
29;9(1):2098. doi: 10.1038/s41467-018-04362-x.)

Evangelou E, Warren HR, Mosen-Ansorena D, et al: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. (Nat Genet. 2018 Oct;50(10):1412-1425. doi: 10.1038/s41588-018-0205-x)

Franceschini N, Giambartolomei C, de Vries PS, et al: GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. (Nat Commun. 2018 Dec 3;9(1):5141. doi: 10.1038/s41467-018-07340-5.)

Geirsson A, Ahlsson A, Franco-Cereceda A, Fuglsang S, Gunn J, Hansson EC, Hjortdal V, Jarvela K, Jeppsson A, Mennander A, Nozohoor S, Olsson C, Pan E, Wickbom A, Zindovic I, Gudbjartsson T.: Hospital volumes and later year of operation correlates with better outcomes in acute Type A aortic dissection. (Eur J Cardiothorac Surg 2018:53(1):276-281. doi: 10.1093/ejcts/ezx231)

Hernesniemi J, Heiskanen J, Ruohonen S, Kartiosuo N, Hutri-Kähönen N, Kähönen M, Jokinen E, Tossavainen P, Kallio M, Laitinen T, Lehtimäki T, Viikari JSA, Juonala M, Raitakari OT: Aortic sinus diameter in middle age is associated with body size in young adulthood. (Heart 2018:104(9):773-778. doi: 10.1136/heartjnl-2017-312136)

Hokkanen M, Järvinen O, Huhtala H, Laurikka J.: The effect of obesity on long-term survival and health-related quality of life after coronary artery bypass grafting: a 12-year follow-up. (Coron Artery Dis. 2018 Aug;29(5):378-383. doi: 10.1097/MCA.0000000000000622.)

Holm NR, Andreasen LN, Walsh S, Kajander OA, Witt N, Eek C, Knaapen P, Koltowski L, Gutiérrez-Chico JL, Burzotta F, Kockman J, Ormiston J, Santos-Pardo I, Laanmets P, Mylotte D, Madsen M, Hjort J, Kumsars I, Råmunddal T, Christiansen EH.: Rational and design of the European randomized Optical Coherence Tomography Optimized Bifurcation Event Reduction Trial (OCTOBER). (Am Heart J. 2018 Nov;205:97-109. doi: 10.1016/j.ahj.2018.08.003. Epub 2018 Aug 16)

Jackson VE, Latourelle JC, Wain LV, et al: Meta-analysis of exome array data identifies six novel genetic loci for lung function. (Wellcome Open Res. 2018 Jan 12;3:4. doi: 10.12688/wellcomeopenres.12583.3)

Jalanko M, Heliö T, Mustonen P, Kokkonen J, Huhtala H, Laine M, Jääskeläinen P, Tarkiainen M, Lauerma K, Sipola P, Laakso M, Kuusisto J, Nikus K.: Novel electrocardiographic features in carriers of hypertrophic cardiomyopathy causing sarcomeric mutations. (J Electrocardiol. 2018 Nov – Dec;51(6):983-989. doi: 10.1016/j.jelectrocard.2018.07.009)

Jiang X, O’reilly P, Aschard H, et al: Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. (Nat Commun 2018:9(1):260. doi: 10.1038/s41467-017-02662-2)

Juhola M, Joutsijoki H, Penttinen K, Aalto-Setälä K.: Detection of genetic cardiac diseases by Ca2+ transient profiles using machine learning methods. (Sci Rep. 2018
Jun 19;8(1):9355. doi: 10.1038/s41598-018-27695-5)

Järvelä K, Porkkala H, Karlsson S, Martikainen T, Selander T, Bendel: Postoperative Delirium in Cardiac Surgery Patients. (J Cardiothorac Vasc Anesth 2018:32(4):1597-1602. doi: 10.1053/j.jvca.2017.12.030)

Järvelä K, Rantanen M, Kööbi T, Huhtala H, Sisto T.: Hypertonic saline-hydroxyethyl starch solution attenuates fluid accumulation in cardiac surgery patients: a randomized controlled double-blind trial. (Anaesthesiol Intensive Ther. 2018;50(2):122-127. doi: 10.5603/AIT.2018.0019.)

Järvelä KM, Khan NK, Loisa EL, Sutinen JA, Laurikka JO, Khan JA.: Hyperglycemic Episodes Are Associated With Postoperative Infections After Cardiac Surgery. (Scand J Surg. 2018 Jun;107(2):138-144. doi: 10.1177/1457496917731190)

Kaivosoja TP, Liu S, Dijkstra J, Huhtala H, Sheth T, Kajander OA.: Comparison of visual assessment and computer image analysis of intracoronary thrombus type by optical coherence tomography. (PLoS One. 2018 Dec 17;13(12):e0209110. doi: 10.1371/journal.pone.0209110)

Kettunen J, Ritchie SC, Anufrieva O, Lyytikäinen LP, Hernesniemi J, Karhunen PJ, Kuukasjärvi P, Laurikka J, Kähönen M, Lehtimäki T, Havulinna AS, Salomaa V, Männistö S, Ala-Korpela M, Perola M, Inouye M, Würtz P.: Biomarker Glycoprotein Acetyls Is Associated With the Risk of a Wide Spectrum of Incident Diseases and Stratifies Mortality Risk in Angiography Patients. (Circ Genom Precis Med. 2018 Nov;11(11):e002234. doi: 10.1161/CIRCGEN.118.002234)

Khan JA, Lehtomäki AI, Toikkanen VJ, Ukkonen MT, Nevalainen RM, Laurikka JO.: Long-Term Prognosis and Causes of Death After Pleural Infections. (Scand J Surg 2018:107(2):145-151. doi: 10.1177/1457496917738868)

Khan N, Lyytikäinen L, Khan J, Seppälä I, Lehtomäki A, Kuorilehto T, Suominen V, Lehtimäki T, Oksala N.: Extended Serum Lipid Profile Predicting Long-Term Survival in Patients Treated for Abdominal Aortic Aneurysms. (World J Surg 2018:42(4):1200-1207)

Koivula K, Eskola M, Viikilä J, Lilleberg J, Huhtala H, Birnbaum Y, Nikus K.: Outcome of all-comers with STEMI based on the grade of ischemia in the presenting ECG. (J Electrocardiol. 2018 Jul – Aug;51(4):598-606. doi: 10.1016/j.jelectrocard.2018.03.014)

Lin H, van Setten J, Smith AV, et al: Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval. (Circ Genom Precis Med. 2018 May;11(5):e002037. doi: 10.1161/CIRCGEN.117.002037)

Liu Y, Pérez-Riera AR, Barbosa-Barros R, Daminello-Raimundo R, de Abreu LC, Nikus K, Baranchuk A.: Severe hypercalcemia from multiple myeloma as an acquired cause of short QT. (J Electrocardiol. 2018 Nov – Dec;51(6):939-940. doi: 10.1016/j.jelectrocard.2018.07.020)

Mennander AA.: Should prostacyclin be wrapped inside a fatty flap? (J Thorac Cardiovasc Surg. 2018 Jul;156(1):242-243. doi: 10.1016/j.jtcvs.2018.02.068)

Mennander AA.: Downregulated suppression to obtain upregulated reprogramming. (J Thorac Cardiovasc Surg. 2018 Aug;156(2):566-567. doi: 10.1016/j.jtcvs.2018.03.083)

Mennander AA.: Stepping down from the ivory tower: Inviting the patient for mutual responsibility. (J Thorac Cardiovasc Surg. 2018 Oct;156(4):1496-1497. doi: 10.1016/j.jtcvs.2018.04.038)

Mennander AA.: Time to celebrate! (J Thorac Cardiovasc Surg 2018:155(4):1659-1660. doi: 10.1016/j.jtcvs.2017.11.041)

Mennander AA.: All Patients Are to be Treated Equal — But Are Some More Equal Than Others? (J Invest Surg 2018:31(3):241-242. doi: 10.1080/08941939.2017.1291773)

Mäki AJ, Verho J, Kreutzer J, Ryynänen T, Rajan D, Pekkanen-Mattila M, Ahola A, Hyttinen J, Aalto-Setälä K, Lekkala J, Kallio P.: A Portable Microscale Cell Culture System with Indirect Temperature Control. (SLAS Technol. 2018 Dec;23(6):566-579. doi: 10.1177/2472630318768710)

Niemi R, Roos M, Harmoinen M, Partanen K, Suominen T.: Appreciative management assessed by physiotherapists working in public or private sector: A cross-sectional study. (Physiother Res Int. 2018 Oct;23(4):e1724. doi: 10.1002/pri.1724)

Niinimäk E, Pynnönen V, Kholova I, Paavonen T, Mennander A.: Neovascularization with chronic inflammation characterizes ascending aortic dissection. (Anatol J Cardiol. 2018 Nov;20(5):289-295. doi: 10.14744/AnatolJCardiol.2018.42223)

Nikus K, Pérez-Riera AR, Konttila K, Barbosa-Barros R.: Electrocardiographic recognition of right ventricular hypertrophy. (J Electrocardiol. 2018 Jan – Feb;51(1):46-49. doi: 10.1016/j.jelectrocard.2017.09.004)

Nordenswan HK, Lehtonen J, Ekström K, Kandolin R, Simonen P, Mäyränpää M, Vihinen T, Miettinen H, Kaikkonen K, Haataja P, Kerola T, Rissanen TT, Kokkonen J, Alatalo A, Pietilä-Effati P, Utriainen S, Kupari M.: Outcome of Cardiac Sarcoidosis Presenting With High-Grade Atrioventricular Block. (Circ Arrhythm Electrophysiol. 2018 Aug;11(8):e006145. doi: 10.1161/CIRCEP.117.006145)

Paajanen H, Helanterä I, Kaartinen K, Nikus K, Eskola M, Groop PH, Koskinen P.: Electrocardiographic changes before and after successful kidney transplantation and associations with cardiovascular and mortality outcomes. (Clin Transplant. 2018 May;32(5):e13242. doi: 10.1111/ctr.13242)

Paci M, Pölönen RP, Cori D, Penttinen K, Aalto-Setälä K, Severi S, Hyttinen J.: Automatic Optimization of an in Silico Model of Human iPSC Derived Cardiomyocytes Recapitulating Calcium Handling Abnormalities. (Front Physiol. 2018 Jun 26;9:709. doi: 10.3389/fphys.2018.00709)

Pajamäki N, Metso S, Hakala T, Ebeling T, Huhtala H, Ryödi E, Sand J, Jukkola-Vuorinen A, Kellokumpu-Lehtinen P, Jaatinen P.: Long-term cardiovascular morbidity and mortality in patients treated for differentiated thyroid cancer. (Clin Endocrinol (Oxf). 2018 Feb;88(2):303-310. doi: 10.1111/cen.13519)

Pan E, Gudbjartsson T, Ahlsson A, Fuglsang S, Geirsson A, Hansson EC, Hjortdal V, Jeppsson A, Järvelä K, Mennander A, Nozohoor S, Olsson C, Wickbom A, Zindovic I, Gunn J.: Low rate of reoperations after acute type A aortic dissection repair from The Nordic Consortium Registry. (J Thorac Cardiovasc Surg. 2018 Sep;156(3):939-948. doi: 10.1016/j.jtcvs.2018.03.144)

Potapov I, Latukka J, Kim J, Luukko P, Aalto-Setälä K, Räsänen E.: Information transfer in QT-RR dynamics: Application to QT-correction. (Sci Rep. 2018 Oct 9;8(1):14992. doi: 10.1038/s41598-018-33359-1)

Prajapati C, Ojala M, Aalto-Setälä K.: Divergent effects of adrenaline in human induced pluripotent stem cell-derived cardiomyocytes obtained from hypertrophic cardiomyopathy. (Dis Model Mech 2018:26(11):2. doi: 10.1242/dmm.032896)

Prajapati C, Pölönen RP, Aalto-Setälä K.: Simultaneous recordings of action potentials and calcium transients from human induced pluripotent stem cell derived cardiomyocytes. (Biol Open. 2018 Jul 16;7(7). pii: bio035030. doi: 10.1242/bio.035030)

Pérez-Riera AR, Barbosa-Barros R, Daminello-Raimundo R, de Abreu LC, Tonussi Mendes JE, Nikus K.: Left posterior fascicular block, state-of-the-art review: A 2018 update. (Indian Pacing Electrophysiol J. 2018 Nov – Dec;18(6):217-230. doi: 10.1016/j.ipej.2018.10.001)

Pérez-Riera A, Barbosa-Barros R, Fernandes Silva E Sousa Neto A, Daminello-Raimundo R, de Abreu LC, Nikus K.: Transient prominent anterior QRS forces in the setting ST segment elevation coronary syndrome: Left septal fascicular block. (J Electrocardiol 2018:51(5):798-800. doi: 10.1016/j.jelectrocard.2018.06.006)

Pérez-Riera AR, Barbosa-Barros R, Daminello-Raimundo R, de Abreu LC, Nikus K.: Transient left septal fascicular block in a patient with stable effort angina and critical proximal obstruction of left anterior descending coronary artery. (J Electrocardiol. 2019 Jan – Feb;52:79-81. doi: 10.1016/j.jelectrocard.2018.11.004)

Pölönen RP, Penttinen K, Swan H, Aalto-Setälä K.: Antiarrhythmic Effects of Carvedilol and Flecainide in Cardiomyocytes Derived from Catecholaminergic Polymorphic Ventricular Tachycardia Patients. (Stem Cells 2018:12(2018):9109503. doi: 10.1155/2018/9109503)

Raatikainen MJP, Penttilä T, Korhonen P, Mehtälä J, Lassila R, Lehto M.: The quality of warfarin therapy and CHA2DS2-VASc score associate with the incidence of myocardial infarction and cardiovascular outcome in patients with atrial fibrillation: data from the nationwide FinWAF Registry. (Eur Heart J Cardiovasc Pharmacother. 2018 Oct 1;4(4):211-219. doi: 10.1093/ehjcvp/pvy009)

Rinne P, Guillamat-Prats R, Rami M, Bindila L, Ring L, Lyytikäinen LP, Raitoharju E, Oksala N, Lehtimäki T, Weber C, van der Vorst EPC, Steffens S.: Palmitoylethanolamide Promotes a Proresolving Macrophage Phenotype and Attenuates Atherosclerotic Plaque Formation. (Arterioscler Thromb Vasc Biol 2018:38(11):2562-2575. doi: 10.1161/ATVBAHA.118.311185)

Rinne P, Lyytikäinen LP, Raitoharju E, Kadiri JJ, Kholova I, Kähönen M, Lehtimäki T, Oksala N.: Pro-opiomelanocortin and its Processing Enzymes Associate with Plaque Stability in Human Atherosclerosis – Tampere Vascular Study. (Sci Rep 2018:8:15078. doi: 10.1038/s41598-018-33523-7)

Roselli C, Chaffin MD, Weng LC, et al: Multi-ethnic genome-wide association study for atrial fibrillation. (Nat Genet. 2018 Sep;50(9):1225-1233. doi: 10.1038/s41588-018-0133-9)

Ryödi E, Metso S, Huhtala H, Välimäki M, Auvinen A, Jaatinen P.: Cardiovascular Morbidity and Mortality After Treatment of Hyperthyroidism with Either Radioactive Iodine or Thyroidectomy. (Thyroid 2018:28(9):1111-1120. DOI: 10.1089/thy.2017.0461)

Sawhney JP, Kothiwale VA, Bisne V, Durgaprasad R, Jadhav P, Chopda M, Vanajakshamma V, Meena R, Vijayaraghavan G, Chawla K, Allu J, Pieper KS, John Camm A, Kakkar AK; GARFIELD-AF Investigators: Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry. (Indian Heart J. 2018 Nov – Dec;70(6):828-835. doi: 10.1016/j.ihj.2018.09.001)

Schwartz GG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, Edelberg JM, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Lecorps G, Mahaffey KW, Moryusef A, Pordy R, Quintero K, Roe MT, Sasiela WJ, Tamby JF, Tricoci P, White HD, Zeiher AM; ODYSSEY OUTCOMES Committees and Investigators: Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome. (N Engl J Med. 2018 Nov 29;379(22):2097-2107. doi: 10.1056/NEJMoa1801174)

Solismaa A, Kampman O, Lyytikäinen LP, Seppälä N, Viikki M, Mononen N, Lehtimäki T, Leinonen E: Genetic Polymorphisms Associated With Constipation and Anticholinergic Symptoms in Patients Receiving Clozapine. (J Clin Psychopharmacol. 2018 Jun;38(3):193-199. doi: 10.1097/JCP.0000000000000885)

Soltani A, Lahti J, Järvelä K, Curtze S, Laurikka J, Hokka M, Kuokkala VT: An Optical Method for the In-Vivo Characterization of the Biomechanical Response of the Right Ventricle. (Sci Rep. 2018 May 1;8(1):6831. doi: 10.1038/s41598-018-25223-z)

Strässler ET, Aalto-Setälä K, Kiamehr M, Landmesser U, Kränkel N.: Age Is Relative-Impact of Donor Age on Induced Pluripotent Stem Cell-Derived Cell Functionality. (Front Cardiovasc Med. 2018 Jan 25;5:4. doi: 10.3389/fcvm.2018.00004)

Takeuchi F, Akiyama M, Matoba N, et al: International Genomics of Blood Pressure (iGEN-BP) Consortium Interethnic analyses of blood pressure loci in populations of East Asian and European descent. (Nat Commun. 2018 Nov 28;9(1):5052. doi: 10.1038/s41467-018-07345-0)

Toikkanen V, Rinne T, Nieminen R, Moilanen E, Laurikka J, Porkkala H, Tarkka M, Mennander AA.: Aprotinin Impacts 8-Isoprostane after Coronary Artery Bypass Grafting. (Scand J Surg. 2018 Dec;107(4):329-335. doi: 10.1177/1457496918766720)

Trajanoska K, Morris JA, Oei L, Zheng HF, Evans DM, Kiel DP, Ohlsson C, Richards JB, Rivadeneira F; GEFOS/GENOMOS consortium and the 23andMe research team: Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study. (BMJ. 2018 Aug 29;362:k3225. doi: 10.1136/bmj.k3225)

Tuohinen SS, Keski-Pukkila K, Skyttä T, Huhtala H, Virtanen V, Kellokumpu-Lehtinen PL, Raatikainen P, Nikus K.: Radiotherapy-induced Early ECG Changes and Their Comparison with Echocardiography in Patients with Early-stage Breast Cancer. (Anticancer Res 2018:38(4):2207-15)

Tuohinen SS, Rankinen J, Skyttä T, Huhtala H, Virtanen V, Kellokumpu-Lehtinen PL, Raatikainen P, Nikus K.: Associations between ECG changes and echocardiographic findings in patients with acute non-ST elevation myocardial infarction. (J Electrocardiol 2018:51(2):188-194. doi: 10.1016/j.jelectrocard.2017.11.007)

Tuohinen S, Skyttä T, Poutanen T: Syövän hoitojen sydänvaikutukset. (Suomen Lääkäril 2018:73(19):1207-1212) (ei ebstraktia)

Turcot V, Lu Y, Highland HM, et al: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. (Nat Genet. 2018 Jan;50(1):26-41. doi: 10.1038/s41588-017-0011-x. Erratum in: Nat Genet. 2018 Mar 16;:. Nat Genet. 2018 Mar 16)

Tynkkynen J, Chouraki V, van der Lee SJ, Hernesniemi J, Yang Q, Li S, Beiser A, Larson MG, Sääksjärvi K, Shipley MJ, Singh-Manoux A, Gerszten RE, Wang TJ, Havulinna AS, Würtz P, Fischer K, Demirkan A, Ikram MA, Amin N, Lehtimäki T, Kähönen M, Perola M, Metspalu A, Kangas AJ, Soininen P, Ala-Korpela M, Vasan RS, Kivimäki M, van Duijn CM, Seshadri S, Salomaa V.: Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer’s disease: A prospective study in eight cohorts. (Alzheimers Dement. 2018 Jun;14(6):723-733. doi: 10.1016/j.jalz.2018.01.003)

van der Lee SJ, Teunissen CE, Pool R: Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies. (Alzheimers Dement. 2018 Jun;14(6):707-722. doi: 10.1016/j.jalz.2017.11.012. Erratum in: Alzheimers Dement. 2019 Feb;15(2):319)

van Setten J, Brody JA, Jamshidi Y, et al: PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. (Nat Commun. 2018 Jul 25;9(1):2904. doi: 10.1038/s41467-018-04766-9)

Vanninen SUM, Leivo K, Seppälä EH, Aalto-Setälä K, Pitkänen O, Suursalmi P, Annala AP, Anttila I, Alastalo TP, Myllykangas S, Heliö TM, Koskenvuo JW: Heterozygous junctophilin-2 (JPH2) p.(Thr161Lys) is a monogenic cause for HCM with heart failure. (PLoS ONE 2018:13(9):e0203422. doi: 10.1371/journal.pone.0203422)